Saxenda, Ozempic, and Mounjaro all come up when people research weight loss injections. They share a family resemblance but differ in ingredient, dosing, and action. Here is how they line up.

In this article

Saxenda

Saxenda contains liraglutide, a GLP-1 medication. Its main practical difference is that it is a daily injection rather than weekly. It works on the same appetite and fullness pathway as the others, reducing hunger and helping you feel satisfied with less. Some people prefer the daily routine, while others find a weekly option easier to keep up.

Ozempic

Ozempic contains semaglutide and is a once-weekly injection. It acts on the single GLP-1 pathway and has a strong track record for both blood sugar control and weight loss. For many people the weekly schedule is simpler to maintain than a daily one.

Mounjaro

Mounjaro contains tirzepatide and is also a once-weekly injection. It is the dual-action option, working on both GLP-1 and a second hormone called GIP. In studies this combined approach produced larger average weight loss at higher doses for many participants.

Side by side

Saxenda is daily liraglutide on one pathway. Ozempic is weekly semaglutide on one pathway. Mounjaro is weekly tirzepatide on two pathways.

All three reduce appetite, all three are doctor-only medicines, and all three share a broadly similar side effect profile of mild nausea and digestive changes that usually ease over time. The differences that matter most in practice are the dosing schedule, the strength of effect, availability, and cost.

Choosing with a doctor

There is no single best option for everyone. The right choice depends on your health history, your other medication, how your body responds, your preference for daily versus weekly, and what is available and affordable. A registered doctor weighs all of this and recommends the most appropriate medicine, then adjusts if your response or circumstances change.

Thinking about GLP-1 weight loss?

Our registered doctors assess your full picture before recommending anything. Start with a free three minute eligibility check.

Start your assessment
This article is general health information and is not a substitute for personal medical advice. Medication should only be taken under the guidance of a registered doctor who has assessed your individual health. Speak to a doctor before starting or changing any treatment.